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viewing the chromosomes that founded a selfing species

In our new paper (published in PLoS genetics) I use patterns within and among founding haplotypes to learn about the the selfing plant, Capsella rubella.

Selfing plants reproduces predominantly by fertilizing their eggs with their own pollen. The ecological and evolutionary impacts of this mode of reproduction (including the impact of selfing on establishment, and invasions, the ”purging” of the genetic load, and the relaxation of intragenomic conflicts in a homozygous genome) are among the ideas that first got me super excited about science.

Because patterns of variation across the genome contain information about species’ history, population  genomic data offers promise towards helping us understand these questions. Because selfing increases homozygosity and ultimately decreases the effective recombination rate, genomes of selfing plants consist of long chunks of ancestry (‘haplotypes’), only rarely broken up by ancestral recombination events. By finding contiguous regions of the genome where individuals are identical at sites polymorphic in the population ancestral to C. rubella, we identified long haplotypes representing long stretches of ancestry descended form a chromosome that founded this species. We used patterns of variation within and among these founding haplotypes to (1) learn how many individuals founded the species, (2) document an ‘out-of-Greece’ population bottleneck, (3) observe a relaxation in purifying selection since the origin of selfing and  and (4) find a remarkably stable population size in Greece over the last ~ 10k years.

for more read our paper

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About Yaniv Brandvain

I'm a population geneticist in the department of plant biology at the university of minnesota

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news

(10/11/17) -- In our new paper Heath Blackmon shows that sexually antagonistic selection can lead to the breakdown of Y chromosomes by favoring inversions that cause aneuploidy.

(9/14/17) -- Postdoc Adam on the unusual S locus of Leavenworthia in New Phytologist [paper].

(9/1/17) -- (former :( ) Postdoc Heath Blackmon starts as an assistant professor at Texas A&M.

(8/30/17) -- Annual lab trip to the state fair! [pic].

(7/1/17) -- Our paper showing that self‐compatibility is over‐represented on islands is out in New Phytologist [link].

(5/1/17) -- It's fun to be the popgen / natural variation part of a team aiming to domesticate Silphium . See our master plan and rational in our Crop Science paper.

(2/6/17) -- Yaniv is Honored to be named a McKnight Land Grant Professor. Read the college announcement here.

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